Details for gene set BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS[GSEA]

Table: GSEA Results Summary

Dataset	set03_truncNotch_versus_wtNotch
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS
Enrichment Score (ES)	0.606003
Normalized Enrichment Score (NES)	1.575434
Nominal p-value	0.027777778
FDR q-value	0.43239617
FWER p-Value	0.999

Fig 1: Enrichment plot: BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GNAQ	64	3.955	0.2527	Yes
2	AGT	743	2.472	0.3764	Yes
3	PPP1R14A	807	2.429	0.5302	Yes
4	CCL4	2079	1.796	0.5782	Yes
5	CCL11	3302	1.443	0.6060	Yes
6	CXCL12	5563	0.972	0.5475	No
7	F2	6888	0.729	0.5235	No
8	PRKCA	9829	0.161	0.3759	No
9	EDN1	12601	-0.473	0.2576	No
10	PLCB1	14453	-1.013	0.2237	No

Fig 2: BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS: Random ES distribution
Gene set null distribution of ES for BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS